By Nikki A. Ford, John DiGiovanni, Stephen D. Hursting (auth.), Mikhail G. Kolonin (eds.)

Recent experiences have proven that cells from adipose tissue are able to trafficking to tumors, therefore allowing paracrine motion of adipokines from in the tumor microenvironment. elevated tumor vascularization, immune process suppression and direct results on malignant telephone survival and proliferation were investigated as mechanisms regulated by means of adipokines. The target of this booklet is to debate info pointing to the position of adipose tissue in melanoma and to dissect person mechanisms by which adipose tissue extra or limit may possibly impact melanoma progression.

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Postdiagnosis BMI was not found to be associated with overall mortality, cancer-specific mortality, or cardiovascular disease-specific mortality. These studies have direct clinical implications, since diet and exercise can be modified and it has been shown that cancer patients are motivated and capable of adjusting their lifestyle and dietary habits [57]. However, it is too early to tell if losing weight after being diagnosed with colon cancer will decrease the mortality risk. 5 Adipose Progenitor Cells A possible link between obesity and cancer, which has so far been overlooked, relates to White Adipose Tissue (WAT) as a source of progenitor cells that could promote tumorigenesis and cancer progression.

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27. Roxburgh CS et al. Relationship between preoperative comorbidity, systemic inflammatory response, and survival in patients undergoing curative resection for colorectal cancer. Ann Surg Oncol. 2011;18:997–1005. 28. Slattery ML et al. Diet and survival of patients with colon cancer in Utah: is there an association? Int J Epidemiol. 1989;18:792–7. 29. Prizment AE, Flood A, Anderson KE, Folsom AR. Survival of women with colon cancer in relation to precancer anthropometric characteristics: the Iowa Women’s Health Study.

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Adipose Tissue and Cancer by Nikki A. Ford, John DiGiovanni, Stephen D. Hursting (auth.),
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