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Extra resources for Advances in Cancer Research, Vol. 28
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They will also be more subject to a variety of other errors including a “switch on” of deeply repressed potentialities such as a program of synthesis of a protein hormone never produced in the ancestral cell line. With the development of overt malignancy, the susceptibility to error of all sorts seems to mount to any level that still remains compatible with viability as virtual parasite of the host. This is the phenomenon of progression, and if our approach is sound, the clones selected for capacity to survive and overgrow their congeners will also pick up more or less at random a variety of other characteristics.
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