By Kai-Uwe Lewandrowski

Advances in Spinal Fusion finds a brand new iteration of fabrics and units for more desirable operations in spinal fusion. This reference showcases rising learn and applied sciences in parts corresponding to biodegradable implants, drug supply, stem telephone isolation and transfection, cellphone encapsulation and immobilization, and the layout of 2nd and 3D scaffolds for cells. It captures a cascade of techniques an important to elevated therapeutic and reduced morbidity in spinal fusion equipment and mechanics and addresses present criteria in analytical method and quality controls, it describes the choice of biomaterials for superior biocompatibility, biostability, and structure/function relationships.

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Reversal of vertebral deformities in osteoporosis: measurement error or ‘‘rebound’’? J. Bone Miner. Res 1994; 9:977–982. 32 Belkoff 61. Lieberman IH, Dudeney S, Reinhardt MK, Bell G. Initial outcome and efficacy of ‘‘kyphoplasty’’ in the treatment of painful osteoporotic vertebral compression fractures. Spine 2001; 26:1631–1638. 62. Jasper LE, Deramond H, Mathis JM, Belkoff SM. Material properties of various cements for use with vertebroplasty. J. Mater. Sci. Mater. Med 2002; 13:1–5. 63. Cotten A, Boutry N, Cortet B, Assaker R, Demondion X, Leblond D, Chastanet P, Duquesnoy B, Deramond H.

17. Gangi A, Kastler BA, Dietemann JJ. Percutaneous vertebroplasty guided by a combination of CT and fluoroscopy. Am. J. Neuroradiol 1994; 15:83–86. 18. Zoarski GH, Snow P, Olan WJ, Stallmeyer MJB, Dick BW, Hebel R, De Deyne M. Percutaneous vertebroplasty for osteoporotic compression fractures: quantitative prospective evaluation of longterm outcomes. J. Vasc. Interv. Radiol 2002; 13:139–148. 19. Al-Assir I, Perez-Higueras A, Florensa J, Munoz A, Cuesta E. Percutaneous vertebroplasty: a special syringe for cement injection.

V. INDICATIONS A. Kyphoplasty 1. As a Pain-Relieving Procedure A major complaint of patients with osteoporotic VCFs is pain. This pain can become progressive and intractable, affecting the patient’s ability to perform his or her daily activities. As a vertebral augmentation procedure, kyphoplasty is indicated for progressive or intractable pain associated with an osteoporotic VCF. In recent clinical series, greater than 90% of patients reported longstanding pain relief after surgery [1,2,22]. The most likely mechanism of pain relief is fracture stabilization, provided by the injected polymethylmethacrylate bone cement.

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Advances in Spinal Fusion: Molecular Science, Biomechanics, by Kai-Uwe Lewandrowski
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