By Joseph Panno
Makes an attempt to appreciate the getting older method have generated numerous theories yet few useful cures. conventional cures deal with age-related ailments comparable to melanoma and arthritis yet don't opposite the getting older procedure itself. a typical development in gerontology is to look for genes that experience a demonstrable impact on lifespan, the so-called durability genes. Many such genes were pointed out, and even though the manipulation of those genes doesn't cease the getting older strategy, they supply many worthy insights into the mobile mechanisms of getting older. extra lately, curiosity has grew to become to using cloning expertise, stem cellphone research, and genetic manipulation for you to produce a good rejuvenation treatment for cells and the physique as an entire.
getting older, Revised version describes the sector of gerontology and the numerous theories that scientists have constructed through the years to provide an explanation for the age-related alterations that take place in approximately all animals.
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Extra info for Aging. Modern theories and therapies
If it can be done in one cell, it could be done in many. And if all the nuclei in an old person’s body could be reprogrammed to a youthful phenotype, it would lead to the complete rejuvenation of all the cells in the body. If that happened, the individual would grow younger. This possibility will be discussed in chapter 8. The Road Ahead In 1900 life expectancy for the average North American was only 45 years. This has increased to the current expectancy of 80 years primarily because of a dramatic reduction in infant mortality, cures for various diseases, better hygiene, and better living conditions.
In addition, what scientists have learned about animal cloning and stem cells since 1996 suggests that it may indeed be possible to produce a therapy that will allow an individual to grow younger. Growing younger, at the cellular level, is analogous to the reprogramming of a cloned cell nucleus: Both are a matter of converting a cell from an aged phenotype (the physical expression of an organism’s genes) to a youthful phenotype. In a sense the cloning The Quest for Immortality 13 of a cell nucleus is the most successful attempt at rejuvenation that has yet been accomplished.
At the population level, long-lived individuals can be compared to their Aging Characteristics 35 short-lived brethren in the hope of identifying the factors that are responsible for the difference, and at the same time shed some light on the nature of the aging process itself. A similar strategy may also be applied at the cellular and tissue levels. Some cells or tissues may age more rapidly than others simply because the body places a greater demand on their time; as a consequence, they are forced to be extremely active and thus burn out more quickly.
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