By M.V. Nermut and A.C. Steven (Eds.)

Animal Virus constitution presents a entire, state of the art precis of the constitution, molecular composition, and valuable antigenic and organic homes of every presently famous family members of animal viruses. info deriving from electron microscopy, laptop photo processing and X-ray diffraction is built-in systematically with biochemical facts into 3-dimensional molecular versions of viral structure. a short account of virus/cell interplay and pathogenicity completes every one bankruptcy.

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27-39. Williams and Wilkins, Baltimore. D. (1980) Movement and self-control in protein assemblies. Quasi-equivalence revisited. Biophys. J . 32, 103-108. R. (1950) Principles and problems of biological growth. Sci. Mon. 70, 376-389. C. D. (1956) The structure of small viruses. Nature (London) 177,473-475. J. and Haguenau, F. (1973) Ultrastructure of animal viruses and bacteriophages. An Atlas. Academic Press, New York and London. V. and Rentier, B. (1984) Assembly of enveloped RNA viruses. Springer Verlag, Vienna, New York.

Res. 89, 111-122. M. R. (1968) Regulation of glutamine synthetase. XII. Electron microscopy of the enzyme from Escherichza coli. Biochemistry 7, 2143-2152. C. (1953a) A method of freeze-drying for electron microscopy. Exp. Cell Res. 4, 188-201. C. (1953b) The shapes and sizes of purified viruses as determined by electron microscopy. Cold Spring Harbor Symp. Quant. Biol. 18, 185-196. V. V. J. HOCKLEY2 and H. , and "Robert Koch lnstitut, Nordufer 20, loo0 Berlin 65, Germany Interactions of viruses with the host cell comprise their adsorption to the cell surface (in most cases via specific receptors), uptake and transport in the cytoplasm, followed by uncoating and release of the genome, nucleic acid replication, and finally synthesis of virus proteins leading to the assembly of new virus progeny.

Principle of triangulation. The basic triangular facet of the icosahedron (A) is subdivided into 4 triangles (B), or 9 (C) or 16 (D) or 25 (E). The triangulation numbers are consequently 1, 4, 9, 16 and 25 and the numbers of subdivisions on an edgefequal 1, 2, 3, 4 and 5 . There is no direct relationship between the triangulation number and the size of the virion, but viruses with higher T numbers tend to be larger. 13 0 1 2 3 4 5 6 7 9 8 1 0 1 1 1 2 1 3 1 4 H + Fig. 7. Triangulation numbers (in circles) ( T =H 2 H K + K 2 )represented on an equilateral triangular net (Goldberg triangle).

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Animal Virus Structure by M.V. Nermut and A.C. Steven (Eds.)
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