By Atta-ur-Rahman

The e-book includes articles written through major professionals of their respective fields of study. It provides present frontiers and destiny directions for examine in accordance with vital discoveries made within the box of bioactive normal products.- quantity 28 is a part of an exceptional family members of worthy reference books- Illustrates the categories of severe discoveries that emerge from the interface of chemistry and biology- Contributions are from well-respected authors

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The chloroform extracts were usually subjected to fractionation over silica gel columns with CHCI3MeOH gradients, followed by reversed phase HPLC, Lobar on C-18 and RP-18 columns with MeOH-H20 mixtures as the eluents. Fractionation of the CHCb-MeOH 9:1 and MeOH extracts was conducted by gel filtration over Sephadex LH-20 using MeOH as eluent sometimes preceded by partition of the extracts between A2-butanol and H2O. The Sephadex LH20 fractions were finally purified by RP-HPLC, Lobar RP-8 and/or RP18, and flash column chromatography.

2. 39 |ig/mL. 7. 3 ^iM. 9 ^M, respectively. 4. 'Activity found as a constituent of Broussonetia kazinofd. ^Antiproliferation activity shown by the inhibition of ['H]thymidine incorporation into DNA in the proliferation of rat vascular smooth muscle cells. 4. ''Activity found as a constituent of a plant other than a Broussonetia species. Broussochalcone A (32) [48], a prenylated chalcone, is one of the most completely studied constituents of B. papyrifera biologically. 8 |aM as well as induction by adrenaline in human platelet-rich plasma.

Chem. , 1984, 689-692. ; Botta, B. Phytochemistry, 1995,39,575-580. ; Nakanishi, K. Heterocycles, 1981, 75, 1163-1170. ; Cheih, C. Phytochemistry, 1990,29,2738-2740. E. Phytochemistry, 1982,21,2107-2109. ; Namba, T. Phytochemistry, 1995, 40, 945-947. ; Okuda, T. Chem. Pharm. Bull, 1988, 36, 2090-2097. N. , 1983,24, 3013-3016. ; Sii2aiki, T. Agric. , 1991,55,1333-1341. -N. , 1999, 62, 1033-1035. -N. Phytochemistry, 1997, 44, 943-947. M. Tetrahedron, 1991, 47, 79918000. S. Phytochemistry, 1989,28,3564-3566.

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Bioactive Natural Products (Part I) by Atta-ur-Rahman
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