By Zhang You-Hui (auth.), Professor Dr. med. Gustav Wagner, Professor Zhang You-Hui (eds.)

To stimulate better German-Chinese cooperation within the box of oncology, the Ger­ guy melanoma study middle (DKFZ) carried via a "Chinese-German Sympo­ sium on melanoma of the Liver, the Esophagus, and the Nasopharynx" in Heidelberg from three to five July 1985. those 3 sorts of melanoma have been selected as they're super infrequent in Europe yet essentially the most often chanced on varieties in China. nearly half the approximately 260000 situations of basic liver melanoma happening every year around the globe are chinese language; of the approximately 300000 esophagus cancers happening each year, greater than part are chinese language; nasopharyngeal melanoma is approximately a hundred occasions extra common between chinese language humans than in Caucasians. below those conditions, it's not miraculous that the chinese language visitor audio system of the Heidelberg symposium - chosen experts within the 3 subsections of oncolo­ gy pointed out - have been capable of record approximately huge reports with sufferer popu­ lations of a measurement hardly ever that you can imagine in Europe. the good scientific event of the chinese language site visitors was once supplemented by way of targeted contributions of eu specialists. therefore, this quantity allows a topical survey of the state-of-the-art in those 3 can­ cers, with subsections of epidemiology, pathology, and medical therapy. The editors desire to thank the Federal Ministry of analysis and know-how (BMFT) for his or her encouragement and direct assist in getting ready and wearing during the symposium, the administration Board of the DKFZ for his or her beneficiant guidance and Springer-Verlag for the e-book and perfect creation of this volume.

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Some weeks after the appearance of the first glycogen storage cells, the majority of the pronounced glycogen storage foci show, in addition to this alteration, decreased activity of glycogen phosphorylase and of glucose-6-phosphatase, while the activity of glucose6-phosphate dehydrogenase, the key enzyme of the pentose phosphate pathway, increases [29]. More detailed quantitative studies of the glucose-6-phosphate dehydrogenase revealed that there is a gradual increase in enzyme activity from the small glycogenotic foci, which show only a tendency to higher values, via the large glycogenotic to mixed cell foci [37].

Invest. 44 (1981) 252- 264 11. : Hepatocellular glycogenosis and related pattern of enzymatic changes during hepatocarcinogenesis. Adv. Enzyme Reg. 22 (1984) 97 -121 12. Bannasch P, Klinge 0: Hepatozellulare Glykogenose und Hepatombildung beim Menschen. Virchows Arch. Abt. A 352 (1971) 157 -164 13. : Potential significance of phenotypic instability in focal and nodular liver lesions induced by hepatocarcinogens. In H. Brunner, H. 191-209. New York: Raven Press 1985 14. Bannasch P, Reiss W: Histogenese und Cytogenese cholangiocellularer Tumoren bei Nitrosomorpholin-vergifteten Ratten.

But the problem of why Chongming Island has a much higher PLC mortality rate than many other counties in China and why the PLC mortality rate of eastern Chongming Island is significantly higher than that of western Chongming Island remains unsolved. As shown in Table 3, study participants living in Kongyan, a commune situated in the eastern part of this island, had the highest PLC incidence rate but the lowest HBV carrier rate. The PLC incidence rates between subjects living in different communes showed no statistical differences among noncarriers but among HBV carriers; the PLC rate of those who lived in Kongyan commune was significantly higher than that of the other three communes.

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Cancer of the Liver, Esophagus, and Nasopharynx by Zhang You-Hui (auth.), Professor Dr. med. Gustav Wagner,
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