By John Ziebuhr (Eds.)

Coronaviruses, the newest quantity within the Advances in Virus Research sequence first released in 1953, covers a various diversity of in-depth experiences, delivering a worthy assessment of the sphere. This sequence is a priceless source for virologists, microbiologists, immunologists, molecular biologists, pathologists, and plant researchers.

  • Contains contributions from prime professionals in virus research
  • Provides accomplished stories for normal and professional use
  • Presents the 1st and longest-running assessment sequence in virology

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2014. IFITM proteins inhibit entry driven by the MERS-coronavirus spike protein: evidence for cholesterol-independent mechanisms. Viruses 6 (9), 3683–3698. 3390/v6093683. , 2009. Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor. Proc. Natl. Acad. Sci. A. 106 (47), 19970–19974. 0908837106. , 2003. The SARS-CoV S glycoprotein: expression and functional characterization. Biochem. Biophys. Res. Commun. 312 (4), 1159–1164. S0006291X03024136 [pii].

Shedding of S1 probably requires receptor binding as well as proteolytic processing at S1/S2. The cryo-EM structure indicates that the S1/S2 proteolytic cleavage site is accessible to proteases prior to spike–receptor interaction, and depending on the particular cleavage site present may already be processed in the cell in which the virions are produced. As indicated earlier, the conformational changes in the S protein that result in virus-cell fusion most likely also require cleavage at the S20 site immediately upstream of the fusion peptide.

M408782200 [pii]. , 2007. Role of the coronavirus E viroporin protein transmembrane domain in virus assembly. J. Virol. 81 (7), 3597–3607. 01472-06. 01472-06 [pii]. , 2000. Strategy for systematic assembly of large RNA and DNA genomes: transmissible gastroenteritis virus model. J. Virol. 74 (22), 10600–10611. , 2003. Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus. Proc. Natl. Acad. Sci. A. 100 (22), 12995–13000. 1735582100. , 2005. Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice.

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Coronaviruses by John Ziebuhr (Eds.)
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